Foudroyant Course of an Extensive Clostridium septicum Gas Gangrene in a Diabetic Patient with Occult Carcinoma of the Colon
نویسندگان
چکیده
Background. Spontaneous gas gangrene is a rare disease in which Clostridium septicum frequently can be detected. After an incubation period of 5-48 hours, a very painful swelling is accompanied by a rapidly spreading toxic-infectious clinical picture ultimately leading to septic shock and multiple organ failure. We present a case of a completely documented rare infectious disease with triage findings including initial vital signs, initial medical findings, and the emergency lab., radiological, intraoperative, histopathological, microbiological, and postmortem results. After initial diagnosis of the underlying disease, the patient has been immediately transferred to the operating theatre. The laboratory findings reflect the devastating effect of toxin α which is a toxin typically produced by C. septicum. The patient presented both an anaemia and a manifest coagulopathy as well as an onset of multiple organ failure. Despite the aggressive medical and surgical measures that have been taken, this patient could not be saved. Discussion. The case presented vividly emphasises the difficulty to identify these cases early enough to save a patient. This documentation may help health care providers to identify this life threatening disease as early as possible in future cases.
منابع مشابه
Myonecrosis secondary to Clostridium Septicum in a patient with Occult Colon Malignancy: a case report
BACKGROUND Gas gangrene is a relatively rare event that is typically associated with history of trauma. A non-traumatic history of gas gangrene has been associated with Clostridium septicum and cecal malignancy. CASE PRESENTATION We present a case of a 54-year-old male patient who presented with myonecrosis secondary to Clostridium septicum septicemia and an occult cecal carcinoma. CONCLUSI...
متن کاملSpontaneous fulminant gas gangrene.
Gas gangrene is a rare condition, usually associated with contaminated traumatic injuries. It carries a high rate of mortality and morbidity. A number of studies have implicated non-traumatic gas gangrene and colonic neoplasia. This paper reports a patient who presented spontaneously with Clostridium septicum gas gangrene and an occult caecal carcinoma.
متن کاملExcruciating thigh pain and hepatic air collection.
CT findings (figures 1 and 2) were consistent with infection of a liver metastasis as a result of gas-producing bacteria. Culture specimens grew C. septicum. The patient died 28 h after onset of symptoms despite intensive medical treatment. Clostridium species are anaerobic, gram-positive, spore-forming bacteria. Clostridial infections are believed to be more prevalent among patients with malig...
متن کاملSimultaneous necrotizing soft tissue infection and colonic necrosis caused by Clostridium septicum.
BACKGROUND Clostridial myonecrosis is an uncommon, highly lethal necrotizing soft tissue infection. The source may be occult at the time of clinical presentation. In cases caused by Clostridium septicum, there is an association with colorectal malignant disease, suggesting that underlying colonic pathology frequently is the source of the infection. METHODS Case report and literature review. ...
متن کاملClostridium septicum Gas Gangrene in Colon Cancer: Importance of Early Diagnosis
The Clostridia species are responsible for some of the deadliest diseases including gas gangrene, tetanus, and botulism. Clostridium septicum is a rare subgroup known to cause atraumatic myonecrosis and is associated with colonic malignancy or immunosuppression. It is a Gram-positive, anaerobic, spore-forming bacillus found in the gastrointestinal tract and can lead to direct, spontaneous infec...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
عنوان ژورنال:
دوره 2013 شماره
صفحات -
تاریخ انتشار 2013